The development of a national quality infrastructure needs always to be oriented towards the local specifics. This statement is especially true for small countries and island states. Mesopartner has had the privilege of accompanying national quality policies (NQPs) in several of these countries. Our first experience was the NQP of Trinidad and Tobago, followed by NQP’s for Antigua and Barbuda, Grenada and Suriname. We are currently advising the Government of Saint Kitts and Nevis to develop the NQP for one of the world’s smallest countries. In addition, we guide the process of identifying and analysing the need for quality infrastructure services in the Pacific Islands region.